Side-Effects of Prozac

As with most prescription drugs, there are side-effects to taking Prozac ranging from nuisance, to mild, to severe. The nuisance side-effects are more common and least threatening to your health. The severe side-effects can be potentially life threatening if not taken care of. Use this information in supplement with your doctor or other health professionals advice and not in substitution.

Although Prozac is mainly used for depression, there have been reported cases of depression and other symptoms actually worsening after taking Prozac along with anxiety, sleep, anger, and mental stability issues. Contact your doctor immediately if your symptoms worsen. Prozac should never be prescribed for someone with clinical bi-polar disorder.

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Side Effects
Precautions Interactions / Contraindications

Side Effects

While taking Prozac you may MILD experience side-effect symptoms including:

    Decreased Appetite
    Lethargy and general lack of energy
    Excessive Yawning

These symptoms are normal and non-life threatening. However, if they become worse, notify your doctor/health professional.

While taking Prozac, although rare, you may experience SEVERE side effects. If any of these are present contact your doctor immediately.

    Angry, Irritable, or High Energy Moods
    Thoughts of suicide, other self-harm, or harm to others.
    Bruising / Bleeding becomes more apparent.
    Uncontrolled muscle spasms or weakness
    Decreased libido (sex drive)
    Sexual performance or ability changes
    Unexplained weight loss

If you experience any of the following rare side effects, seek medical help IMMEDIATELY:

    Bloody or tar-like stool
    Dark colored vomit
    Urine volume change
    Any other serious body changes

    Other Side Effects -

    Diabetics may want to monitor their blood sugar levels more closely while on Prozac. Fluoxetine has a history of affecting blood sugar levels. Tell you doctor if this happens.

    Although rare, a patient may get Serotonin Syndrome while taking Prozac. Serotonin Syndrome occurs when there is too much Serotonin in the brain. If you become anxious, restless, have a loss of balance and coordination, fever, nausea, diarrhoea, fast heartbeat, and twitching muscles you may be experiencing Serotonin Syndrome. Get immediate help if this happens.

    Serotonin may increase the chance of erection in men. If an erection lasts longer than four hours, call your doctor or health professional.

    Like many drugs, Prozac runs the risk of being an allergen. If you experience any allergic reactions such as trouble breathing, rash, itching, swelling, or dizziness, seek help immediately.


    There are certain things to make sure of before starting your Prozac treatment. Failure to recognize these precautions can result in injury, illness, disorders, or very rarely, death.

      Do not stop treatment unless specifically instructed by your doctor.
      Do not skip doses. If you miss a dose for whatever reason, do not double dose. Wait for the next time to take your pill and continue as usual.
      Heavy machinery such as any moving vehicle should not be operated under the effects of Prozac if you become dizzy or disoriented.
      Do not drink alcohol along with your treatment of Prozac. Alcohol only stands to worsen depression anyway.
      Make sure to alert your doctor or medical professional about your medical history. Make sure they are aware if you have any allergies, specifically an allergy to Fluoxetine, history of seizures, ulcers, or low sodium. Alert them if you have been diagnosed with bi-polar disorder. Prozac should NOT be used on someone with Bi-polar disorder.
      Tell your doctor about any medications you are taking or have recently took. This includes prescription, non-prescription, and herbal supplements/vitamins.
      It's been known for Prozac to seep into breast milk. Taking this drug while pregnant or after pregnancy should be discussed with your doctor.
      OVERDOSE: As long as you are taking your prescription there is no need to worry about overdosing on Prozac. The LD50 of Prozac has been show in lab mice to be 284mg taken orally. LD50 means Lethal Dosage at 50%. This means that 50% of lab mice died at this dosage. If you think you've overdosed contact help immediately.

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